A simple and sensitive test developed by i-sense engineers at Imperial College London, in collaboration with MIT, has produced a colour change in urine to signal growing tumours in mice.
In light of technology advances, a recent publication in Nature Microbiology, updates the current benchmark that describes the ideal diagnostic test, taking into consideration the need to achieve the Sustainable Devel
A recent study, published in Journal of Virological Methods, suggests and evaluates a modification to a currently used lab-based diagnostic test for dengue. The improved test has shown it can reduce the likelihood of false negatives and increase identification of a specific type of the virus.
The combination of mobile devices with diagnostic tools offers new possibilities to test, track and treat infectious diseases as well as improve health systems, according to a new review published today in Nature.
A huge congratulations to i-sense Deputy Director, Prof Molly Stevens, for being elected Foreign Member of the National Academy of Engineering (NAE), when earlier this month the NAE elected 86 new members and 18 foreign members.
On the 12 & 13 December, the Africa Health Research Institute (AHRI) hosted the m-Africa workshop in Durban. The project is a two-year Medical Research Council GCRF Foundation Award that started in April 2017. m-Africa has allowed researchers from University College London, Imperial College London, and AHRI to work together to evaluate the feasibility of introducing mobile phone-connected tools to improve access to HIV testing, as well as linkage to care, in KwaZulu-Natal.
With the help of a Patient Public Involvement Starter Grant from the NIHR University College London Hospitals Biomedical Research Centre, Dr Harriet Gliddon, an i-sense Postdoc in the McKendry group, held a consultation with people who are living with HIV to understand how i-sense research developing a rapid test for HIV viral load could be used by individuals in the home and link them to digital healthcare systems.
A new review from i-sense members, published in AIDS, looks at the last 20 years of research around diagnostics that use p24, an important protein in the detection of early stage HIV.
New research from the McKendry group at UCL, published in Digital Medicine, reports a pilot clinical study using a shear horizontal surface acoustic wave (SH-SAW) biosensors based on low-cost components found in smartphones to diagnose HIV in 133 patients.
TwistDx Ltd, based in Cambridge UK, has developed an isothermal DNA amplification technology, Recombinase Polymerase Amplification (RPA), which offers PCR-like sensitivity within 10 minutes of reaction time. RPA is easy to operate using pre-formulated stable reagents, needs minimal sample processing and requires no thermocycler. RPA products can be detected by methods including electrophoresis, lateral flow strips or real-time fluorescence.
